Differences

This shows you the differences between two versions of the page.

--- results [2015/12/22 17:46] – created mhidalgo
+++ results [2017/05/24 15:27] (current) – external edit 127.0.0.1
@@ Line 5: / Line 5: @@
 Each time the //Update// button on the //Gene list// panel is pressed, **a comparison is performed** with the modifications present in the Gene list and the Additional drug targets.
-Pathways with signaling differences are depicted in bold characters in the //Pathway list// panel. The **up and down arrows** indicate that there exist up- and down-regulated subpaths in the corresponding pathways, respectively. When the up arrow is red or the down arrow is blue, the differences are significant. An absolute fold change greater than 2 is considered significant. Therefore, an absolute log fold change greater than log(2)= 0.6931472 is considered significant.
+Pathways with signaling differences are depicted in bold characters in the //Pathway list// panel. The **up and down arrows** indicate that there exist up- and down-regulated circuits in the corresponding pathways, respectively. When the up arrow is red or the down arrow is blue, the differences are significant. An absolute fold change greater than 2 is considered significant. Therefore, an absolute log fold change greater than log(2)= 0.6931472 is considered significant.
-Subpaths with signaling differences are depicted in bold characters in the //Subpath list// panel. The up and down arrows indicate that the subpath is up- or down-regulated, respectively. When the up arrow is red or the down arrow is blue, the differences are significant.
+{{ :results_pathway.png?200 |}}
+Circuits with signaling differences are depicted in bold characters in the //Circuit list// panel. The up and down arrows indicate that the circuit is up- or down-regulated, respectively. When the up arrow is red or the down arrow is blue, the differences are significant.
+{{ :results_circuit.png?200 |}}
+Results can be also visualized in the //Pathway viewer// in a graphical way. Each time a pathway is selected in the //Pathway List// it is displayed in the //Pathway viewer//. The edges of the circuits with a difference in their activation are depicted in different colors.
+  * **Light greyish red**: The circuit is up-regulated, but not significantly.
+  * **Light greyish blue**: The circuit is down-regulated, but not significantly.
+  * **Red**: The circuit is significantly up-regulated.
+  * **Blue**: The circuit is significantly down-regulated.
+{{ :ege_colors.png?200 |}}
 The results can be exhaustively examined and downloaded from the **report generated** by pressing the //Show report// button. A new window with the report of the results for the current comparison is displayed. This report includes two fields:
@@ Line 13: / Line 25: @@
   * **Input**: Lists the genes whose expression has been modified in the current comparison, and the new expression value.
   * **Path impact**: Lists the names of the pathways, ordered by the absolute value of their fold change (also log(Fold_Change)). An absolute fold change greater than 2 is considered significant. Therefore, an absolute log fold change greater than log(2)= 0.6931472 is significant.
-In order to close this window and return to the tool page, you can press the x button on the right upper side of the window.
+{{ :results_report.png?600 |}}
+In order to close this window and return to the tool page, you can press the close button on the right upper side of the window.